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Chlorambucil is a drug which is used to treat many kinds of cancer. It is a
brown tablet that you take by mouth.
EARLY SIDE EFFECTS: Nausea and vomiting occur rarely when you take
chlorambucil tablets. If these are a problem for you, the physician may
give you a prescription for antinausea medication which should be taken
as directed. Antinausea medication is more effective when used to prevent
nausea than when used to treat it after it has occurred. Appropriate food
choices can help to control your nausea.
DELAYED SIDE EFFECTS: White blood cells (that fight infection) and
platelets (that help your blood to clot) will start decreasing about one
week after you start taking chlorambucil. This is a normal and expected
response. Regular blood tests are done to monitor your blood counts.
Other medications may interact with chlorambucil. Do not start taking new
medications without first checking with your physician or pharmacist. For
minor pain, use acetaminophen (Tylenol); do not use ASA (Aspirin) or
ibuprofen (Advil). Inform your physicians and dentists that you are taking
chlorambucil before you receive treatment from them. It is important to
take chlorambucil exactly as ordered by your physician. Make sure you
understand the directions. Unless you are directed differently, you should
take your total daily dose of chlorambucil at one time, 30 minutes to one
hour before eating. Store chlorambucil tablets at room temperature, out of
the reach of children. It is important to drink 2-3 litres (8-12 cups) of
fluid daily.
Use birth control while taking this drug and for at least four months after
you stop taking it. Do not breast feed during treatment.
NOTIFY YOUR PHYSICIAN IMMEDIATELY IF ANY OF THE FOLLOWING OCCUR:
- Signs or symptoms of an infection such as fever (over 100F or 38C),
cold symptoms, cough, pain or swelling of any areas of the body,
ulceration or abscess (pus) forming anywhere on the body.
- Easy bleeding or bruising.
Tell your physician as soon as possible (during office hours)
if you have:
- Shortness of breath, difficulty breathing or a cough.
- lower back or side pain.
- signs of gout such as joint pain.
- changes in eyesight.
- Uncontrolled nausea, vomiting or diarrhea.
Store this medication in its original labelled container in the
refrigerator, out of the reach of children.
REPORT ANY ADDITIONAL PROBLEMS TO YOUR PHYSICIAN.
